TRP-601_product_DataBase

Bioactivity	TRP-601 is a caspase inhibitor. TRP-601 reversed the increased expression of active caspase-2, the activation of endogenous apoptotic pathway and the up-regulation of key protein triggered by hyperoxia[1].
In Vivo	TRP-601 (1 mg/kg, Intraperitoneal injection, single dose) 减少高氧诱导的大鼠半胱氨酸天冬氨酸蛋白酶激活，减轻大鼠发育期大脑神经元细胞死亡和抑制内源性凋亡信号[1]。 Animal Model:
Name	TRP-601
CAS	1094569-02-4
Formula	C40H48F2N6O11
Molar Mass	826.84
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. M Sifringer, et al. Prevention of neonatal oxygen-induced brain damage by reduction of intrinsic apoptosis. Cell Death Dis. 2012 Jan 12;3(1):e250. [2]. Sifringer M, et al. Prevention of neonatal oxygen-induced brain damage by reduction of intrinsic apoptosis [J]. Cell death & disease, 2012, 3(1): e250-e250.

PeptideDB