Bioactivity | G6PI 325-339 (human) hydrochloride 是 B10.Q 小鼠关节炎的有效诱导剂。G6PI 325-339 (human) hydrochloride 引发 Th1 和 Th17 细胞与鼠 G6PI 蛋白的交叉反应。G6PI 325-339 (human) hydrochloride 通过 T 和 B 细胞依赖性途径诱导关节炎模型,但没有抗体效应机制。 |
Name | G6PI 325-339 (human) (hydrochloride) |
Sequence | Ile-Trp-Tyr-Ile-Asn-Cys-Phe-Gly-Cys-Glu-Thr-His-Ala-Met-Leu |
Shortening | IWYINCFGCETHAML |
Formula | C82H118ClN19O21S3.xHCl |
Molar Mass | 1801.12 (free base) |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Angela Pizzolla, et al. A glucose-6-phosphate isomerase peptide induces T and B cell-dependent chronic arthritis in C57BL/10 mice: arthritis without reactive oxygen species and complement. Am J Pathol. 2013 Oct;183(4):1144-1155. |