| Bioactivity | TRAF6 peptide is a specific TRAF6-p62 inhibitor. TRAF6 peptide potently abrogates NGF-dependent TrkA ubiquitination. TRAF6 peptide has good research potential in neurological diseases such as alzheimer's disease (AD), parkinson's, ALS, head trauma, epilepsy and stroke[1]. |
| Invitro | TRAF6 peptide (150 µM; 5 h) blocks the interaction of p62 with TRAF6 in PC12 cells[1].TRAF6 peptide eliminates TRAF6 and UbcH7 from interacting with TrkA and can ffectively abolish NGF-dependent ubiquitination of TrkA in vitro[1]. Western Blot Analysis[1] Cell Line: |
| Name | TRAF6 peptide |
| CAS | 852805-92-6 |
| Shortening | AAVALLPAVLLALLAPESASGPSEDPSVNFLK |
| Formula | C145H238N34O44 |
| Molar Mass | 3161.64 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |