| Bioactivity | Presenilin 1 (349-361) is an active petide, and synthetic peptides representing amino acids 349–361 can be phosphorylated by glycogen synthase kinase-3β(GSK3β) in vitro. Presenilin 1 (349-361) can be used for the research of various diseases[1]. |
| Invitro | Presenilin 1 (349-361) reduces the interaction with beta-catenin leading to decreased phosphorylation and ubiquitination of beta-catenin when structural change, thereby increases its nuclear signaling and the transcription of target genes, including c-MYC[1]. |
| Name | Presenilin 1 (349-361) |
| CAS | 956004-39-0 |
| Shortening | GPHRSTPESRAAV |
| Formula | C56H93N21O19 |
| Molar Mass | 1364.47 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Presenilin 1 (349-361)
CAS: 956004-39-0 F: C56H93N21O19 W: 1364.47
Presenilin 1 (349-361) is an active petide, and synthetic peptides representing amino acids 349–361 can be phosphorylat
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