| Bioactivity | TPI-287, a blood-brain barrier-permeable microtubule stabilizer, can significantly reduce metastatic colonization of breast cancer in the brain[1]. |
| In Vivo | TPI-287 (i.v., 18 mg/kg, every 4 days, 41 days) 在接种了 231-BR 乳腺癌细胞的小鼠肿瘤模型中，可以有效减小肿瘤体积，抑制肿瘤的生长[1]。 |
| Name | TPI-287 |
| CAS | 849213-15-6 |
| Formula | C46H63NO15 |
| Molar Mass | 869.99 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Daniel P Fitzgerald, et al. TPI-287, a new taxane family member, reduces the brain metastatic colonization of breast cancer cells. Mol Cancer Ther. 2012 Sep;11(9):1959-67. |