| Bioactivity | TMV-IN-1, chalcone derivative, is a tobacco mosaic virus (TMV) inhibitor. TMV-IN-1 has good therapeutic activity and protective activity against TMV with EC50 values of 70.7 μg/mL and 60.8 μg/mL, respectively. TMV-IN-1 can be used for the research of infection, inflammation and tumor[1]. |
| Target | EC50: 70.7 μg/mL, 60.8 μg/mL(TMV)Kd: 0.0427 μM (TMV-CP). |
| Invitro | TMV-IN-1 (compound N2) 对 TMV 具有良好的治疗活性和保护活性，EC50 值分别为 70.7 μg/mL 和 60.8 μg/mL[1].TMV-IN-1 可结合 TMV 外壳蛋白 (TMV-CP)，Kd 值为 0.0427 μM[1]。TMV-IN-1 (5-7days) 降低丙二醛的增加速率，增加防御酶的含量[1]。 |
| Name | TMV-IN-1 |
| Formula | C28H26O4 |
| Molar Mass | 426.50 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Nan Sun, et al. Design, Synthesis, and Bioactivity of Chalcone Derivatives Containing Indanone. ACS Omega 2023. |