| Bioactivity | TGR5 agonist 1 (compound 18) is a potent TGR5 agonist with an EC50 value of 0.31 µM[1]. |
| Target | IC50: 0.31 µM (TGR5) |
| Name | TGR5 agonist 1 |
| Formula | C28H48NNaO6S |
| Molar Mass | 549.74 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Luxenburger A, et al. The discovery of 12β-methyl-17-epi-18-nor-bile acids as potent and selective TGR5 agonists. Eur J Med Chem. 2023 Mar 15;250:115143. |