| Bioactivity | TG53 is a potent inhibitor of tissue transglutaminase (TG2) and fibronectin (FN) protein-protein interaction. TG53 inhibits formation of a complex with integrin β1 and activation of FAK and c-Src during SKOV3 cell attachment onto FN. TG53 can be used for ovarian cancer research[1]. |
| Name | TG53 |
| CAS | 946369-04-6 |
| Formula | C21H22ClN5O2 |
| Molar Mass | 411.88 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Gary E. Schiltz, et al. Inhibitors of tissue transglutaminase 2 (tg2) and uses thereof. Patent, US20210276960A1. 09/09/2021. |