| Bioactivity | TEAD-IN-10 (compound 15) has good selective activity and inhibitory effect on TEAD1 (IC50=14 nM), TEAD2 (IC50=179 nM) and TEAD3 (IC50=4 nnM) as a covalent inhibitor. TEAD-IN-10 can be used for cancer research[1]. |
| Invitro | TEAD-IN-10 对 MCF-7 报告基因试验有较好的抑制作用 (IC50≤10 nM) [1]。TEAD-IN-10 对 TEAD1 和 TEAD2 具有很好的选择性，在 HEK293T 细胞中分别有 97% 和 98% 的抑制效果[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> TEAD-IN-10 相关抗体: Cell Viability Assay[1] Cell Line: |
| CAS | 3032196-65-6 |
| Formula | C15H14F3NO |
| Molar Mass | 281.27 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Henry William, et al. Yap/taz-tead oncoproteins inhibitors.WO2024059317A1.2023-09-15 |
TEAD-IN-10
CAS: 3032196-65-6 F: C15H14F3NO W: 281.27
TEAD-IN-10 (compound 15) has good selective activity and inhibitory effect on TEAD1 (IC50=14 nM), TEAD2 (IC50=179 nM) an
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