| Bioactivity | HDAC-IN-72 (compound 7j) is the most potent HDAC1(IC50=0.65 ± 0.07 μM), HDAC2(IC50=0.78 ± 0.02 μM), HDAC3(IC50=1.70 ± 0.1 μM) inhibitor and antiproliferative compound. HDAC-IN-72 can be used for breast cancer research[1]. |
| Invitro | HDAC-IN-72 (0.1-50 μM, 48 h) 对乳腺癌细胞株 MCF-7 (IC50=0.83 ± 1.41 μM) 和 T47D (IC50=1.4 ± 1.85 μM) 有较好的抗增殖活性[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> HDAC-IN-72 相关抗体: |
| CAS | 763066-77-9 |
| Formula | C22H21N3O2 |
| Molar Mass | 359.42 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Cheshmazar N, et al. Key structural requirements of benzamide derivatives for histone deacetylase inhibition: design, synthesis and biological evaluation[J]. Future Medicinal Chemistry, 2024 (0). |