| Bioactivity | TDI-11861 is second-generation soluble Adenylyl Cyclase (sAC, ADCY10) inhibitor with slow dissociation rates. TDI-11861 inhibits sAC cellular with an IC50 value of 5.5 nM[1]. |
| Target | IC50: 5.5 nM (soluble Adenylyl Cyclase) |
| Name | TDI-11861 |
| CAS | 2857049-72-8 |
| Formula | C22H25ClF2N6O3 |
| Molar Mass | 494.92 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Miller M, et al. Design, Synthesis, and Pharmacological Evaluation of Second-Generation Soluble Adenylyl Cyclase (sAC, ADCY10) Inhibitors with Slow Dissociation Rates. J Med Chem. 2022 Nov 8. |
TDI-11861
CAS: 2857049-72-8 F: C22H25ClF2N6O3 W: 494.92
TDI-11861 is second-generation soluble Adenylyl Cyclase (sAC, ADCY10) inhibitor with slow dissociation rates. TDI-1186
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