| Bioactivity | TAT-p16 (p16INK4a peptide) is a peptide mimic of p16INK4a that can induce an early G[1] phase cell cycle arrest in the absence of active cyclin E:Cdk2 complex[1]. |
| Invitro | TAT-p16 (10-100 μM; 30 h) 在 人 HaCaT 角质形成细胞中会导致显著的 G1 期细胞周期阻滞[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> TAT-p16 相关抗体: |
| Sequence | Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Asp-Ala-Ala-Arg-Glu-Gly-Phe-Leu-Ala-Thr-Leu-Val-Val-Leu-His-Arg-Ala-Gly-Ala-Arg |
| Shortening | YGRKKRRQRRRGDAAREGFLATLVVLHRAGAR |
| Formula | C159H274N64O40 |
| Molar Mass | 3722.28 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Gius DR, et al. Transduced p16INK4a peptides inhibit hypophosphorylation of the retinoblastoma protein and cell cycle progression prior to activation of Cdk2 complexes in late G1. Cancer Res. 1999 Jun 1;59(11):2577-80. |