| Bioactivity | EGFR T790M/L858R-IN-7 (Compound 72) is a novel pyrimidine compound that inhibits the EGFR T790M and L858R mutation with a high efficacy (93% inhibition rate at 0.05 μM). EGFR T790M/L858R-IN-7 functions by specifically binding to the kinase domain of EGFR, thereby inhibiting its phosphorylation activity[1]. |
| CAS | 3032760-90-7 |
| Formula | C27H29N7O4 |
| Molar Mass | 515.56 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Guoqing Paul C, et al. World Intellectual Property Organization, WO2024064091 A1 2024-03-28 |
EGFR T790M/L858R-IN-7
CAS: 3032760-90-7 F: C27H29N7O4 W: 515.56
EGFR T790M/L858R-IN-7 (Compound 72) is a novel pyrimidine compound that inhibits the EGFR T790M and L858R mutation with
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