| Bioactivity | TAT-MKK3b is a p38 peptide inhibitor. TAT-MKK3b can inhibit p38 phosphorylation. TAT-MKK3b has renal targeting, ROS-scavenging, and ferroptosis-mitigating capabilities. TAT-MKK3b improves acute kidney injury and its progression to chronic kidney disease[1]. |
| CAS | 928163-65-9 |
| Sequence | Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Lys-Gly-Lys-Ser-Lys-Arg-Lys-Lys-Asp-Leu-Arg-Ile |
| Shortening | YGRKKRRQRRRGKGKSKRKKDLRI |
| Formula | C129H240N56O30 |
| Molar Mass | 3055.64 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Xin W, et al. Self-Assembling P38 Peptide Inhibitor Nanoparticles Ameliorate the Transition from Acute to Chronic Kidney Disease by Suppressing Ferroptosis. Adv Healthc Mater. 2024 Sep;13(23):e2400441. |
TAT-MKK3b
CAS: 928163-65-9 F: C129H240N56O30 W: 3055.64
TAT-MKK3b is a p38 peptide inhibitor. TAT-MKK3b can inhibit p38 phosphorylation. TAT-MKK3b has renal targeting, ROS-scav
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