| Bioactivity | TACC3 inhibitor 1 is a potent and cross the blood-brain barrier TACC3 inhibitor. TACC3 inhibitor 1 induces Apoptosis and cell cycle arrest at G2/M phase. TACC3 inhibitor 1 induces the generation of intracellular ROS. TACC3 inhibitor 1 shows antiproliferative and anti-tumor activity[1]. |
| Invitro | TACC3 inhibitor 1 (compound 7g) (1, 2, 4 µM; 36 h) 诱导细胞凋亡和细胞周期停滞在 G2/M 期[1]。TACC3 inhibitor 1 (1, 2, 4 µM; 36 h) 降低线粒体膜电位并诱导细胞内 ROS 的产生[1]。TACC3 inhibitor 1 (1, 2, 4 µM; 24 h) 抑制 U87 细胞的迁移和侵袭[1]。 Cell Proliferation Assay[1] Cell Line: |
| Name | TACC3 inhibitor 1 |
| Formula | C20H21N5OS |
| Molar Mass | 379.48 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |