Bioactivity | T988C is a heptacyclic epidithiodioxopiperazine (ETP) natural product. T988C shows strong cytotoxicity to cultured P388 leukemia cells[1]. |
Invitro | T988C 抑制 P388 白血病细胞,ID50 为 0.56 μM[1]。 |
Name | T988C |
CAS | 823802-57-9 |
Formula | C23H20N4O4S2 |
Molar Mass | 480.56 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. DeLorbe JE, et al. General approach for preparing epidithiodioxopiperazines from trioxopiperazine precursors: enantioselective total syntheses of (+)- and (-)-gliocladine C, (+)-leptosin D, (+)-T988C, (+)-bionectin A, and (+)-gliocladin A. J Am Chem Soc. 2013 Mar 13;135(10):4117-28. [2]. Feng Y, et al. Novel cytotoxic thiodiketopiperazine derivatives from a Tilachlidium sp. J Nat Prod. 2004 Dec;67(12):2090-2. |