| Bioactivity | Sulfisoxazole acetyl (N1-Acetylsulfisoxazole), a Sulfisoxazole derivative, is an orally active dihydropteroate synthase inhibitor. Sulfisoxazole acetyl has an antibacterial action[1]. |
| Invitro | As with other sulfonamides, the antibacterial action of Sulfisoxazole acetyl (N1-Acetylsulfisoxazole) is attributable to inhibiting dihydropteroate synthase, a key enzyme in folate synthesis in bacteria. Sulfisoxazole acetyl is known to be transformed primarily to sulfisoxazole, partly to N4-acetyl sulfisoxazole (N4AS), and likely also to diacetyl sulfisoxazole (DAS) and other compounds[1]. |
| Name | Sulfisoxazole acetyl |
| CAS | 80-74-0 |
| Formula | C13H15N3O4S |
| Molar Mass | 309.34 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Eunyoung Kim, et al. Simultaneous determination of N(1)-acetyl sulfisoxazole and its metabolites, and relative bioavailability compare to sulfisoxazole in rats. J Pharm Biomed Anal. 2016 Sep 10;129:117-120. |
Sulfisoxazole acetyl
CAS: 80-74-0 F: C13H15N3O4S W: 309.34
Sulfisoxazole acetyl (N1-Acetylsulfisoxazole), a Sulfisoxazole derivative, is an orally active dihydropteroate synthase
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