| Bioactivity | Suchilactone (Jatrophan) is a lignan extracted from Monsonia angustifolia E.Mey. Suchilactone binds to SHP2 and inhibits SHP2 activation, thereby inhibiting ERK-mediated cell proliferation. Suchilactone can be ued in acute myeloid leukaemia (AML)[1]. |
| Name | Suchilactone |
| CAS | 50816-74-5 |
| Formula | C21H20O6 |
| Molar Mass | 368.38 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Wu J, et al. Suchilactone inhibits the growth of acute myeloid leukaemia by inactivating SHP2. Pharm Biol. 2022 Dec;60(1):144-153. |
Suchilactone
CAS: 50816-74-5 F: C21H20O6 W: 368.38
Suchilactone (Jatrophan) is a lignan extracted from Monsonia angustifolia E.Mey. Suchilactone binds to SHP2 and inhibits
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