| Bioactivity | Stachybotramide is a natural fungal metabolite with the property of modulating the activity of cholesteryl ester transfer protein (CETP). Stachybotramide stimulates the transfer of cholesteryl esters (CE) from high-density lipoprotein (HDL) to very-low-density lipoprotein (VLDL) and low-density lipoprotein (LDL), increasing the transfer efficiency by 1.3- to 1.5-fold. Stachybotramide slightly reduced the transfer of cholesteryl esters from LDL and VLDL to HDL at 0.5 mM. The effect of Stachybotramide on the transfer of triglycerides (TG) from HDL was not significant. By these results, Stachybotramide was shown to preferentially stimulate the CETP-mediated transfer of cholesteryl esters from HDL to VLDL and LDL[1]. |
| CAS | 149598-71-0 |
| Formula | C25H35NO5 |
| Molar Mass | 429.55 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Modulation of the plasma cholesteryl ester transfer by stachybotramide |
Stachybotramide
CAS: 149598-71-0 F: C25H35NO5 W: 429.55
Stachybotramide is a natural fungal metabolite with the property of modulating the activity of cholesteryl ester transfe
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