| Bioactivity | Spiraeoside, an orally active natural compound, exerts antioxidant activity, inhibits reactive oxygen species (ROS) and malondialdehyde production. Spiraeoside possesses antiallergic, anti-inflammatory and antitumor activities[1]. |
| Invitro | Spiraeoside elevates HG stimulation-caused the decrease in the expression levels of p-Akt, nuclear Nrf2, and HO-1 in AC16 cells (the effects of Spiraeoside are reversedby LY294002)[1]. Spiraeoside protects AC16 cells against HG-induced oxidative stress, cell injury, and apoptosis[1]. Spiraeoside activates the PI3K/Akt/Nrf2 pathway in AC16 cells on exposure to HG[1].Spiraeoside protects AC16 cells against HG-induced apoptosis through the PI3K/Akt/Nrf2 pathway[1]. Cell Viability Assay[1] Cell Line: |
| Name | Spiraeoside |
| CAS | 20229-56-5 |
| Formula | C21H20O12 |
| Molar Mass | 464.38 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |