| Bioactivity | PROTAC BRD4 Degrader-12 (compound 9c) is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. PROTAC BRD4 Degrader-12 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.39 nM and 0.24 nM, respectively[1]. |
| Name | PROTAC BRD4 Degrader-12 |
| CAS | 2417370-90-0 |
| Formula | C62H77F2N9O12S4 |
| Molar Mass | 1306.58 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | -20°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
PROTAC BRD4 Degrader-12
CAS: 2417370-90-0 F: C62H77F2N9O12S4 W: 1306.58
PROTAC BRD4 Degrader-12 (compound 9c) is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. PROTAC BRD4 Degra
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