| Bioactivity | Sphingomyelin phosphodiesterase, a hydrolase, is involved in the sphingomyelin metabolism process. Sphingomyelin phosphodiesterase hydrolyzes the conversion of sphingomyelin to phosphocholine and ceramide. Sphingomyelin phosphodiesterase also plays an important role in cellular differentiation, various immune and inflammatory responses, and intracellular cholesterol trafficking and metabolism[1][2]. |
| Name | Sphingomyelin phosphodiesterase |
| CAS | 9031-54-3 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Rongrong Pan, et al. Chapter Nine-Nanokits for the electrochemical quantification of enzyme activity in single living cells. Methods in Enzymology. Volume 628, 2019, Pages 173-189. [2]. Aykut A, et al. Analysis of the sphingomyelin phosphodiesterase 1 gene (SMPD1) in Turkish Niemann-Pick disease patients: mutation profile and description of a novel mutation. Gene. 2013 Sep 10;526(2):484-6. |