| Bioactivity | SphK2-IN-1 is a SphK2 inhibitor (IC50: 0.359 μM). SphK2-IN-1 can be used in the research of cancer, inflammation, neurological and cardiovascular disorders[1]. |
| Invitro | SphK2-IN-1 (compound 25b, 125 µM, 24 h) inhibits cell viability against U-251 MG human glioblastoma cells[1]. Cell Viability Assay[1] Cell Line: |
| Name | SphK2-IN-1 |
| Formula | C23H22ClF3N8O |
| Molar Mass | 518.92 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Vijai Kumar Reddy Tangadanchu, et al. Structure-activity relationship studies and bioactivity evaluation of 1,2,3-triazole containing analogues as a selective sphingosine kinase-2 inhibitors. Eur J Med Chem. 2020 Nov 15;206:112713. |