| Bioactivity | Axl-IN-9 (Example 10) is a potent AXL inhibitor, with an IC50 of 26 nM. Axl-IN-9 has excellent transmembrane properties. Axl-IN-9 exhibits excellent pharmacokinetic properties in an animal body. Axl-IN-9 can be used for the research of proliferative diseases, autoimmune diseases, allergic diseases, inflammatory diseases, transplant rejection, cancer, or other diseases in mammals[1]. |
| Target | IC50: 26 nM (AXL) |
| Name | Axl-IN-9 |
| CAS | 2487649-73-8 |
| Formula | C25H23N7O2 |
| Molar Mass | 453.50 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Xi Ning. Substituted heteroaryl compound, composition of same, and uses thereof. WO2020182188A1. |
Axl-IN-9
CAS: 2487649-73-8 F: C25H23N7O2 W: 453.50
Axl-IN-9 (Example 10) is a potent AXL inhibitor, with an IC50 of 26 nM. Axl-IN-9 has excellent transmembrane properties.
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