Sinomenine N-oxide_product_DataBase

Bioactivity	Sinomenine N-oxide has anti-angiogenic, anti-inflammatory and anti-rheumatic effects. Sinomenine N-oxide is also a NO production inhibitor, with an IC50 value of 23.04 μM[1][2][3].
Invitro	Sinomenine N-oxide (10-200 μM, 2 h) 抑制 LPS 诱导的 Raw264.7 细胞中的 IL-6 和 TNF-α 水平[3]。
Name	Sinomenine N-oxide
CAS	1000026-77-6
Formula	C19H23NO5
Molar Mass	345.39
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Liu WJ, et al. Network pharmacology approach to elucidate possible action mechanisms of Sinomenii Caulis for treating osteoporosis. J Ethnopharmacol. 2020 Jul 15;257:112871. [2]. Zeng HL, et al. New N-oxide alkaloids from the stems of Sinomenium acutum. Fitoterapia. 2023 Mar;165:105404. [3]. Li Q, et al. Metabolic mechanism and anti-inflammation effects of sinomenine and its major metabolites N-demethylsinomenine and sinomenine-N-oxide. Life Sci. 2020 Nov 15;261:118433.

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