PeptideDB

Simvastatin Acyl-β-D-glucuronide

CAS: 463962-56-3 F: C31H48O12 W: 612.71

Simvastatin Acyl-β-D-glucuronide is a metabolite of Simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA redu
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Bioactivity Simvastatin Acyl-β-D-glucuronide is a metabolite of Simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM[1][2].
Name Simvastatin Acyl-β-D-glucuronide
CAS 463962-56-3
Formula C31H48O12
Molar Mass 612.71
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Prueksaritanont T, Subramanian R, Fang X, et al. Glucuronidation of statins in animals and humans: a novel mechanism of statin lactonization. Drug Metab Dispos. 2002;30(5):505‐512.