Bioactivity | Silatecan (AR-67; DB 67) is a Camptothecin (HY-16560) analogue with improved stability and lipophilicity. Silatecan is an inhibitor for topoisomerase I, that inhibits the DNA replication and transcription, and exhibits antitumor and radiosensitizing activities[1] |
CAS | 220913-32-6 |
Formula | C26H30N2O5Si |
Molar Mass | 478.61 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Chen A Y, et al. Silatecan DB-67 is a novel DNA topoisomerase I–targeted radiation sensitizer[J]. Molecular cancer therapeutics, 2005, 4(2): 317-324. |