| Bioactivity | Scyliorhinin I is a tachykinin-1 (NK-1) and tachykinin-2 (NK-2) receptor agonist with a Ki value of 0.9 nM for rat submandibular gland NK-1 receptor and 2 nM for hamster bladder NK-2 receptor. Scyliorhinin I has the ability to contract the longitudinal muscles of the guinea pig ileum[1][2]. |
| CAS | 103425-21-4 |
| Sequence | Ala-Lys-Phe-Asp-Lys-Phe-Tyr-Gly-Leu-Met-NH2 |
| Shortening | AKFDKFYGLM-NH2 |
| Formula | C59H87N13O13S |
| Molar Mass | 1218.47 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Conlon, et al. "Scyliorhinin I and II: two novel tachykinins from dogfish gut." FEBS letters 200.1 (1986): 111-116. [2]. Stephen H, et al. "The dogfish peptides scyliorhinin I and scyliorhinin II bind with differential selectivity to mammalian tachykinin receptors." European journal of pharmacology 144.1 (1987): 109-111. |
Scyliorhinin I
CAS: 103425-21-4 F: C59H87N13O13S W: 1218.47
Scyliorhinin I is a tachykinin-1 (NK-1) and tachykinin-2 (NK-2) receptor agonist with a Ki value of 0.9 nM for rat subma
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