Bioactivity | Salusin-β is an endogenous bioactive peptide with significant hemodynamic and mitogenic activity. Salusin-β can stimulate the proliferation of quiescent vascular smooth muscle cells (VSMCs) and fibroblasts, leading to a rapid and significant decrease in blood pressure and heart rate. In addition, Salusin-β can stimulate the release of arginine vasopressin from the pituitary gland in rats. This makes Salusin-β have important application potential in cardiovascular disease research[1]. |
CAS | 624735-23-5 |
Sequence | Ala-Ile-Phe-Ile-Phe-Ile-Arg-Trp-Leu-Leu-Lys-Leu-Gly-His-His-Gly-Arg-Ala-Pro-Pro |
Shortening | AIFIFIRWLLKLGHHGRAPP |
Formula | C115H176N32O21 |
Molar Mass | 2342.83 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Shichiri, et al. "Salusins: newly identified bioactive peptides with hemodynamic and mitogenic activities." Nature medicine 9.9 (2003): 1166-1172. |