Bioactivity | STK683963 is a strong activator of cellular ATG4B activity. STK683963 can act as a mediator of redox-regulation of ATG4B in cells. STK683963 can be used for the research of cancer[1]. |
Invitro | STK683963 (0-50 μM) 在 24 小时后以剂量依赖性方式强烈上调荧光素酶释放报告基因[1]。STK683963 强烈激活荧光素酶释放,这在 NAC 存在下被完全阻断[1]。 |
Name | STK683963 |
CAS | 370073-65-7 |
Formula | C12H8FN3O2S |
Molar Mass | 277.27 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Niccolo Pengo, et al. Identification of Kinases and Phosphatases That Regulate ATG4B Activity by siRNA and Small Molecule Screening in Cells. Front Cell Dev Biol. 2018 Nov 1;6:148. |