Laurotetanine_product_DataBase

Bioactivity	Laurotetanine ((+)-Laurotetanine) is an potent and orally active isoquinoline alkaloid and could be extracted from the roots of Litsea cubeba (Lour.) Pers. Laurotetanine exerts an anti-asthmatic effect by inhibition of IgE, histamine, and inflammatory reactions via down-regulating MUC5AC and NF-κB signaling pathways[1].
In Vivo	Laurotetanine ((+)-Laurotetanine; 20-60 mg/kg; p.o.; 每天，持续 21 天; SD 大鼠) 通过下调 MUC5AC 和 NF-κB 信号通路发挥抗哮喘作用。 Animal Model:
Name	Laurotetanine
CAS	128-76-7
Formula	C19H21NO4
Molar Mass	327.37
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Xin XX, et, al. Anti-asthmatic effect of laurotetanine extracted from Litsea cubeba (Lour.) Pers. root on ovalbumin-induced allergic asthma rats, and elucidation of its mechanism of action. TROP J PHARM RES. 2019:18(6).

PeptideDB