Bioactivity | SPSB2-iNOS inhibitory cyclic peptide-3 (Compound CP3) is an inhibitor for the interaction of SPRY domain and SOCS-box protein 2 (SPSB2) and iNOS, through binding SPSB2 on iNOS site with KD of 7 nM[1]. |
CAS | 2244164-71-2 |
Sequence | cyclo{Ile-Asn-Asn-Asn-Abu} |
Shortening | cyclo{INNN-Abu} |
Formula | C22H36N8O8 |
Molar Mass | 540.57 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Sadek MM, et al., A Cyclic Peptide Inhibitor of the iNOS-SPSB Protein-Protein Interaction as a Potential Anti-Infective Agent. ACS Chem Biol. 2018 Oct 19;13(10):2930-2938. |