| Bioactivity | LRRK2-IN-12 (compound 1) inhibits the activity of LRRK2 (G20195)(IC50=0.45 nM), LRRK2 WT (IC50=1.1 nM) and LRRK2 WT ADP-Glo (IC50=0.46 nM). LRRK2-IN-12 can be used for Alzheimer's Disease research[1]. |
| CAS | 3032733-05-1 |
| Formula | C18H17ClN8O2 |
| Molar Mass | 412.83 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Thomas Jensen, et al. Macrocyclic leucine-rich repeat kinase 2 (lrrk2) inhibitors.WO2024056775A1.2023-09-14 |
LRRK2-IN-12
CAS: 3032733-05-1 F: C18H17ClN8O2 W: 412.83
LRRK2-IN-12 (compound 1) inhibits the activity of LRRK2 (G20195)(IC50=0.45 nM), LRRK2 WT (IC50=1.1 nM) and LRRK2 WT ADP-
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