| Bioactivity | SPSB2-iNOS inhibitory cyclic peptide-3 TFA is the TFA salt form of SPSB2-iNOS inhibitory cyclic peptide-3 (HY-P10385). SPSB2-iNOS inhibitory cyclic peptide-3 TFA is an inhibitor for the interaction of SPRY domain and SOCS-box protein 2 (SPSB2) and iNOS, through binding SPSB2 on iNOS site with KD of 7 nM[1]. |
| Sequence | cyclo{Ile-Asn-Asn-Asn-Abu} |
| Shortening | cyclo{INNN-Abu} |
| Formula | C22H36N8O8 |
| Molar Mass | 540.57 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Sadek MM, et al., A Cyclic Peptide Inhibitor of the iNOS-SPSB Protein-Protein Interaction as a Potential Anti-Infective Agent. ACS Chem Biol. 2018 Oct 19;13(10):2930-2938. |
SPSB2-iNOS inhibitory cyclic peptide-3 TFA
CAS: F: C22H36N8O8 W: 540.57
SPSB2-iNOS inhibitory cyclic peptide-3 TFA is the TFA salt form of SPSB2-iNOS inhibitory cyclic peptide-3 (HY-P10385). S
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