| Bioactivity | SPC4061 an antisense nucleotide, sodium is a potent PCSK9 inhibitor. SPC4061 targets the lock-in nucleic acid (LNA) of PCSK9 for the study of hypercholesterolemia and related diseases[1][2]. |
| Name | SPC4061 sodium |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Li Chuan-Yuan, et al. PCSK9 inhibitor compositions and methods for the treatment of cancer associated with PCSK9 expression: World Intellectual Property Organization, WO2020005869 A2 2020-01-02. [2]. Lindholm MW, et al. PCSK9 LNA antisense oligonucleotides induce sustained reduction of LDL cholesterol in nonhuman primates. Mol Ther. 2012 Feb;20(2):376-81. |