| Bioactivity | Cu(II)-Elesclomol is a Cu2+ complex of Elesclomol (HY-12040). Cu(II)-Elesclomol induces apoptosis, causes a G1 cell cycle block and induces DNA double strand breaks in K562 cells. Cu(II)-Elesclomol also weakly inhibits DNA topoisomerase I. Cu(II)-Elesclomol has anticancer activity[1]. | ||||||||||||
| Name | Cu(II)-Elesclomol | ||||||||||||
| CAS | 1224195-72-5 | ||||||||||||
| Formula | C19H18CuN4O2S2 | ||||||||||||
| Molar Mass | 462.05 | ||||||||||||
| Appearance | 固体 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Brian B Hasinoff, et al. Cellular mechanisms of the cytotoxicity of the anticancer drug elesclomol and its complex with Cu(II). hem Pharmacol. 2015 Feb 1;93(3):266-76. [2]. Brian B Hasinoff, et al. Cellular mechanisms of the cytotoxicity of the anticancer drug elesclomol and its complex with Cu(II). hem Pharmacol. 2015 Feb 1;93(3):266-76. |
Cu(II)-Elesclomol
CAS: 1224195-72-5 F: C19H18CuN4O2S2 W: 462.05
Cu(II)-Elesclomol is a Cu2+ complex of Elesclomol (HY-12040). Cu(II)-Elesclomol induces apoptosis, causes a G1 cell cycl
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