| Bioactivity | SP4e is an activator of PPAR-γ, with the EC50 of 739 nM in HK-2 cells. SP4e reduces the blood glucose levels and lipid peroxidation, and increases glutathione levels and catalase activityin the Swiss albino mice[1]. |
| Target | 739 nM (PPAR-γ in the HK-2 cells) |
| Name | SP4e |
| Formula | C22H17ClN2O2S2 |
| Molar Mass | 440.97 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Gupta S, et al. Integrated fragment-based drug design and virtual screening techniques for exploring the antidiabetic potential of thiazolidine-2,4-diones: Design, synthesis and in vivo studies [published online ahead of print, 2023 Sep 21]. Eur J Med Chem. 2023;261:115826. |