Bioactivity | NMS-P945 is an ADC linker that can be used in the synthesis of antibody-drug conjugates (ADCs). NMS-P945 is suitable for conjugation to mAbs with reproducible Drug Antibody Ratio (DAR) >3.5[1]. |
Name | NMS-P945 |
CAS | 1466546-35-9 |
Formula | C61H76ClN11O12S |
Molar Mass | 1222.84 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Valsasina B, Novel thienoduocarmycin-trastuzumab ADC demonstrates Strong Anti-tumor Efficacy with Favorable Safety Profile in Preclinical Studies. Mol Cancer Ther. 2023 Sep 19. |