SORT-PGRN interaction inhibitor 2

CAS: 1008233-79-1 F: C19H31NO W: 289.46

SORT-PGRN interaction inhibitor 2 is a SORT-PGRN inhibitor that can decreases SORT1 protein expression and increases ext

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Bioactivity	SORT-PGRN interaction inhibitor 2 is a SORT-PGRN inhibitor that can decreases SORT1 protein expression and increases extracellular PGRN secretion in mammalian cell lines. SORT-PGRN interaction inhibitor 2 can be used for neurological disease research[1].
Invitro	SORT-PGRN interaction inhibitor 2 (Compound MPEP) ( 0-20 μΜ；24 小时) 在哺乳动物细胞系中降低 SORT1 的表达，增加细胞外 PGRN 分泌[1]。 Western Blot Analysis[1] Cell Line:
Name	SORT-PGRN interaction inhibitor 2
CAS	1008233-79-1
Formula	C19H31NO
Molar Mass	289.46
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Lee WC, et.al. Targeted manipulation of the sortilin-progranulin axis rescues progranulin haploinsufficiency. Hum Mol Genet. 2014 Mar 15;23(6):1467-78.

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