| Bioactivity | SORT-PGRN interaction inhibitor 2 is a SORT-PGRN inhibitor that can decreases SORT1 protein expression and increases extracellular PGRN secretion in mammalian cell lines. SORT-PGRN interaction inhibitor 2 can be used for neurological disease research[1]. |
| Invitro | SORT-PGRN interaction inhibitor 2 (Compound MPEP) ( 0-20 μΜ；24 小时) 在哺乳动物细胞系中降低 SORT1 的表达，增加细胞外 PGRN 分泌[1]。 Western Blot Analysis[1] Cell Line: |
| Name | SORT-PGRN interaction inhibitor 2 |
| CAS | 1008233-79-1 |
| Formula | C19H31NO |
| Molar Mass | 289.46 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lee WC, et.al. Targeted manipulation of the sortilin-progranulin axis rescues progranulin haploinsufficiency. Hum Mol Genet. 2014 Mar 15;23(6):1467-78. |
SORT-PGRN interaction inhibitor 2
CAS: 1008233-79-1 F: C19H31NO W: 289.46
SORT-PGRN interaction inhibitor 2 is a SORT-PGRN inhibitor that can decreases SORT1 protein expression and increases ext
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