| Bioactivity | PROTAC EGFR degrader 8 (T-184) is a PROTAC EGFR degrader. PROTAC EGFR degrader 8 degrades EGFR in HCC827 cell with a DC50 of 15.56 nM. PROTAC EGFR degrader 8 inhibits H1975, PC-9, HCC827 cell growth with IC50s of 7.72 nM, 121.9 nM, 14.21 nM. PROTAC EGFR degrader 8 can be used for research of cancer, especially NSCLC[1]. |
| Name | PROTAC EGFR degrader 8 |
| CAS | 2925923-46-0 |
| Formula | C40H46ClN11O5 |
| Molar Mass | 796.32 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Liang, Apeng, et al. Compounds for EGFR protein degradation and uses thereof.Patent. CN116135852. |
PROTAC EGFR degrader 8
CAS: 2925923-46-0 F: C40H46ClN11O5 W: 796.32
PROTAC EGFR degrader 8 (T-184) is a PROTAC EGFR degrader. PROTAC EGFR degrader 8 degrades EGFR in HCC827 cell with a DC5
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This product is for research use only, not for human use. We do not sell to patients.