Bioactivity | SOICR-IN-1 (compound 32) is a store-overload induced calcium release (SOICR) inhibitor with an IC50 value of 14.6 μM. SOICR-IN-1 can be used for the research of cardiac arrhythmias[1]. | ||||||||||||
Name | SOICR-IN-1 | ||||||||||||
CAS | 1479049-35-8 | ||||||||||||
Formula | C27H28N2O5 | ||||||||||||
Molar Mass | 460.52 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Smith CD, et al. Novel carvedilol analogues that suppress store-overload-induced Ca2+ release. J Med Chem. 2013 Nov 14;56(21):8626-55. |