| Bioactivity | SM27 (NSC 37204) is an inhibitor for fibroblast growth factors (FGF). SM27 inhibits angiogenesis through block of FGF2/HSPGs/FGFR1 complex formation[1]. |
| Invitro | SM27 (0-100 μM, 2 h) 通过抑制 FGF2 介导的细胞-细胞粘附 (IC50为1 mM)，剂量依赖性地抑制 FGF2/肝素和 FGF2/ FGFR1 相互作用[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> SM27 相关抗体: |
| CAS | 6266-54-2 |
| Formula | C21H16N2O9S2 |
| Molar Mass | 504.49 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Pagano K, et al., Direct and allosteric inhibition of the FGF2/HSPGs/FGFR1 ternary complex formation by an antiangiogenic, thrombospondin-1-mimic small molecule. PLoS One. 2012;7(5):e36990. |