| Bioactivity | SIRT3-IN-1 (compound 17f) is a SIRT3 inhibitor, with IC50 of 0.043 μM. SIRT3-IN-1 can be used in the research of acute leukemia (AML)[1]. |
| Formula | C21H19F3N6O2S |
| Molar Mass | 476.47 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yang X, et al. Design, synthesis and biological evaluation of novel SIRT3 inhibitors targeting both NAD+ and substrate binding sites for the treatment of acute myeloid leukemia. Eur J Med Chem. 2024 Oct 5;276:116689. |