| Bioactivity | CENP-E-IN-2 (compound 3) is a photoswitchable CENP-E inhibitor, with the pIC50 of 6.82 without light illumination and 5.85 with 365 nm light illumination. CENP-E-IN-2 has antitumor activity[1]. |
| Formula | C27H33ClN6O4 |
| Molar Mass | 541.04 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kazuya Matsuo, et al. A chemical platform for the efficient screening of arylazopyrazole-based photoswitchable CENP-E inhibitors using mild cyclization reactions. Bioorg Med Chem Lett. 2024 Jul 17:111:129892. |