| Bioactivity | SIIVFEKL TFA is a variant of the major MHC class I-restricted epitope SIINFEKL. SIIVFEKL TFA is an antigenic peptide, that can stimulate specific T cells in experimental settings to study the competitive interaction between T cells. SIIVFEKL TFA exhibits low affinity for the OT-I T cell receptor (TCR), and can be used for detection of CD8+ T cells[1]. | ||||||
| Sequence | Ser-Ile-Ile-Val-Phe-Glu-Lys-Leu | ||||||
| Shortening | SIIVFEKL | ||||||
| Formula | C46H77N9O12.xC2HF3O2 | ||||||
| Molar Mass | 948.16 (free acid) | ||||||
| Appearance | 固体 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
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| Reference | [1]. Petkau G, et al., Zfp36l1 establishes the high-affinity CD8 T-cell response by directly linking TCR affinity to cytokine sensing. Eur J Immunol. 2024 Feb;54(2):e2350700. |
SIIVFEKL TFA
CAS: F: C46H77N9O12.xC2HF3O2 W: 948.16 (free acid)
SIIVFEKL TFA is a variant of the major MHC class I-restricted epitope SIINFEKL. SIIVFEKL TFA is an antigenic peptide, th
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