Bioactivity | SMARCA2/4-degrader-3 (compound I-433) is a PROTAC SMARCA2/4-degrader based on VH032-NH2, with a degradation potency (DC50) <100 nM in MV4-11 cells[1]. |
CAS | 2568507-10-6 |
Formula | C56H66N10O5S |
Molar Mass | 991.25 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Nan J, et al. Smarca degraders and uses thereof, US20230072658A1, 2023-03-09 |