| Bioactivity | SHP2-IN-5 (compound 1) is an inhibitor of SHP2 (IC50: 97 nM). SHP2 is a non-receptor protein tyrosine phosphatase associated with cell growth and proliferation. SHP2-IN-5 has the potential to inhibit cancer and SHP2-related human diseases[1]. |
| Target | IC50: 97 nM (SHP2) |
| Name | SHP2-IN-5 |
| CAS | 54755-93-0 |
| Formula | C12H8O6 |
| Molar Mass | 248.19 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kim B, et al. Development and structure-activity relationship study of SHP2 inhibitor containing 3, 4, 6-trihydroxy-5-oxo-5H-benzo [7] annulene[J]. Bioorganic & Medicinal Chemistry Letters, 2020, 30(1): 126756.. . . |