| Bioactivity | SCH 486757 is an orally effective pain peptide receptor (NOP) agonist. SCH 486757 can be used for the study of cough[1]. |
| In Vivo | SCH 486757 (0.01-1mg/kg, 口服) 在豚鼠辣椒素咳嗽模型中可抑制咳嗽[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
| CAS | 524019-25-8 |
| Formula | C24H23Cl2N3O |
| Molar Mass | 440.36 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. McLeod RL, et al. Pharmacological profile of the NOP agonist and cough suppressing agent SCH 486757 (8-[Bis(2-Chlorophenyl)Methyl]-3-(2-Pyrimidinyl)-8-Azabicyclo[3.2.1]Octan-3-Ol) in preclinical models. Eur J Pharmacol. 2010 Mar 25;630(1-3):112-20. |
SCH 486757
CAS: 524019-25-8 F: C24H23Cl2N3O W: 440.36
SCH 486757 is an orally effective pain peptide receptor (NOP) agonist. SCH 486757 can be used for the study of cough.
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This product is for research use only, not for human use. We do not sell to patients.