Bioactivity | SCD1 inhibitor-4 is a potent, orally active stearoylCoA desaturase-1 (SCD1) inhibitor. SCD1 inhibitor-4 can be used for the research of diabetes[1]. | ||||||||||||
Target | SCD1 | ||||||||||||
In Vivo | SCD1 inhibitor-4 (1~30 mg/kg) shows a dose-dependent decrease in desaturation index with a 55 % reduction at 1 mg/kg and 85% reduction at the 10 and 30 mg/kg doses[1]. | ||||||||||||
Name | SCD1 inhibitor-4 | ||||||||||||
CAS | 1295541-87-5 | ||||||||||||
Formula | C17H16F3N5O | ||||||||||||
Molar Mass | 363.34 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Atkinson KA, et al. N-benzylimidazole carboxamides as potent, orally active stearoylCoA desaturase-1 inhibitors. Bioorg Med Chem Lett. 2011;21(6):1621-1625. |