| Bioactivity | SC-68376 is a potent, reversible, ATP-competitive, and selective inhibitor of p38 MAP kinase inhibitor[1][2][3]. |
| CAS | 318480-82-9 |
| Formula | C15H12N2O |
| Molar Mass | 236.27 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. H. Bosch, et al. Nanoparticulate compositions of mitogen-activated protein (MAP) kinase inhibitors. US20030181411A1. 2005-12-07. [2]. Ermert M, et al. Cyclooxygenase-2-dependent and thromboxane-dependent vascular and bronchial responses are regulated via p38 mitogen-activated protein kinase in control and endotoxin-primed rat lungs. Lab Invest. 2003;83(3):333-347. [3]. Kooijman R, et al. IGF-I stimulates IL-8 production in the promyelocytic cell line HL-60 through activation of extracellular signal-regulated protein kinase. Cell Signal. 2003;15(12):1091-1098. |